HOG COG KOG arCOG COG description NRC-1 annotation
cHOG0342COG0188arCOG04367Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunitDNA gyrase subunit A

HOG Organism Gene ID Name Annotation
cHOG0342 nrc1 VNG0889 gyrA DNA gyrase subunit A
cHOG0342 hmu HMUK2730 Hmuk_2730 DNA gyrase, A subunit( EC:5.99.1.3 )
cHOG0342 hma RRNAC0455 gyrA DNA gyrase subunit A
cHOG0342 hwa HQ2651A gyrA DNA gyrase / DNA topoisomerase II subunit A
cHOG0342 hla HLAC0994 Hlac_994 DNA gyrase, A subunit
cHOG0342 hbo HBOR16520 Hbor_16520 DNA gyrase subunit A( EC:5.99.1.3 )
cHOG0342 hut HUTA0133 Huta_0133 DNA gyrase, A subunit
cHOG0342 hvo HVO_1573 HVO_1573 gyrA DNA gyrase A subunit
cHOG0342 nph NP3500A gyrA DNA gyrase subunit A
cHOG0342 hhi 1180 gyrA DNA gyrase subunit A
MUSCLE (3.6) multiple sequence alignment


3500|gene|nph       MSSDVPDTPDVP---AEEIEPVRIEDEMEQSYIDYAMSVIVGRALPDARDGLKPVQRRIL
889|gene|nrc1       MSSESPDVPDDV---ADRVKNVRVDEEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
133|gene|hut        MSSDVPEGPGVTAD-AARVEHVRIEDEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
10455|gene|hma      MSSDANDANAP----AERIEHVRIEDEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
1180|gene|hhi       MSSDANDANAP----AEQIKHVRIEDEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
994|gene|hla        MSSDVPDADPSDVG-AAQVTNARIEDEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
2651|gene|hwa       MSSDAPERFDPETGIAAEVETARIEREMEQSYIDYAMSVIAGRALPDARDGLKPVHRRIL
16520|gene|hbo      MSSDAPDKFQKDAGIAAEVQNARIEQEMEQSYIDYAMSVIAGRALPDVRDGLKPVHRRIL
                    ***:  :        *  :  .*:: **************.******.*******:****

3500|gene|nph       YAMEEMGVTSRSGHRKSSSIVGETMGNYHPHGDSAIYDALARMAQDFSLRYPLVDGQGNF
889|gene|nrc1       YAMHESGVTSGSGHRKSSNIVGDTMGDYHPHGDSPIYDALVRMAQDFSMRYPLVDGQGNF
133|gene|hut        YAMHEMGVSSGSSHRKSSSVVGEVMGDYHPHGDSAIYDTLVRMAQDFSMRYPLVDGQGNF
10455|gene|hma      YAMHEMGVSSNTAHRKSSSIVGDTMGDYHPHGGSAIYDTLVRMAQDFSMRYPLIDGQGNF
1180|gene|hhi       YAMHEMGVSSNTAHRKSSSIVGDTMGDYHPHGGSAIYDTLVRMAQDFSMRYPLIDGQGNF
994|gene|hla        YAMHEAGVTSNSAHRKSSSVVGETMGDYHPHGDSAIYDTLARMAQDFSMRYPLVDGQGNF
2651|gene|hwa       YAMHQSGISARSAHRKSSSIVGETMGDYHPHGDSAIYNALARMAQDFSMRNPLVDGQGNF
16520|gene|hbo      YAMNEAGVSARSSHRKSSSIVGETMGDYHPHGDSAIYDALARMAQDFSMRYPLVDGQGNF
                    *** : *::: :.*****.:**:.**:*****.*.**::*.*******:* **:******

3500|gene|nph       GSVDGDPPAAMRYTEARMAPIAEELLADIDKDTVDFESNYDDRLTEPVVLPARVPNLLVN
889|gene|nrc1       GSVDGDPAAAMRYTEARMAPIAEELLTDIEKDTVAFQANYDDRLTEPAVLPSSFPNLLVN
133|gene|hut        GSMDGDPAAAMRYTEARMAPIAEELLADIEKDTVDFQANYDDRLEEPEVLPSAFPNLLVN
10455|gene|hma      GSMDGDPAAAMRYTEARMDPLAEELLKDIEKDTVDFSSNYDDRLQEPDVLPSKVPNLLLN
1180|gene|hhi       GSMDGDPAAAMRYTEARMDPIAEELLEDIEKDTVDFSSNYDDRLQEPDVLPSKVPNLLLN
994|gene|hla        GSVDGDPPAAMRYTEARMSPIAEELLADIERDTVDFTSNYDDRLEEPEVLPAAFPNLLVN
2651|gene|hwa       GSVDGDPPAAMRYTEARMSPIAEELLDNIEMDTVEFTANYDDRLSEPAVLPAAFPNLLVN
16520|gene|hbo      GSVDGDPPAAMRYTEARMAPIAEELLEDIDKDTVDFQSNYDDRKQEPVVLPSSFPNLLVN
                    **:****.********** *:***** :*: *** * :*****  ** ***: .****:*

3500|gene|nph       GASGIAVGMSTNIPPHNLGEVIDAAIHLIDNPDCAVADLIDTPDSDGYIKGPDFPTGANI
889|gene|nrc1       GSSGIAVGMSTNVPPHNLGEVIDATIHLIDTPDCTVLDLME------YVKGPDFPTAANI
133|gene|hut        GSSGIAVGMSTNIPPHNLGEVIDATIHLIDNPDAEVTDLME------YVKGPDFPTGANI
10455|gene|hma      GSSGIAVGMSTNIPPHNLGELVDATVHLLGNPDCTVEDLME------HIKGPDFPTGGNI
1180|gene|hhi       GSSGIAVGMSTNIPPHNLGELVNATVQLLENPDCTVEDLME------HIKGPDFPTGGNI
994|gene|hla        GSSGIAVGMSTNIPPHNLGEVIDATVALIKEPDCTVEDLME------HVKGPDFPTGANI
2651|gene|hwa       GSSGIAVGMSTNIPPHNLGEVIDATIHLIHHPECTVEDLMN------HVQGPDFPTGANI
16520|gene|hbo      GSSGIAVGMSTNIPPHNLGEVIDATTHLIENPDCTVEDLME------YVKGPDFPTGANI
                    *:**********:*******:::*:  *:  *:. * **::      :::******..**

3500|gene|nph       VNREGIWDAYTEGRGRLRVRAEMDIERTDRGGDRIVVTELPYQENKARRIERIAEDVQEG
889|gene|nrc1       VGRADVKQAYQTGRGRVRMRAEYHVESNGR-RDSIVITELPYQQNKSTLVERIADDVRDG
133|gene|hut        VGKNAIHAAYATGRGRLTVRAEYEFEETDSGRPRIVITEIPFQENKARMVERIADDVNEG
10455|gene|hma      VGRDAIYSAYATGRGRLRVRAEYEVDPEEG---RIVISELPYQENKARVVERIADDVNEG
1180|gene|hhi       VGRDAIYSAYATGRGRLRVRAEYEVDPEEG---RIVISELPYQENKARVVERIADDVNEG
994|gene|hla        VGRNAVHKAYKTGRGRVRVRAEFEVDEEEG---RIVISELPFQQNKSRLVERIAEDVNDG
2651|gene|hwa       VGQNAIYKAYKTGRGRVRVRAEFDVQDD-----RIVITELPFQTNKARLVERIADNVNAG
16520|gene|hbo      VGKNAVHKAYKTGRGRIRVRAEFEVDEDGD---NIVITELPYQENKARLIERIADDVNDG
                    *..  :  **  ****: :***  .:        **::*:*:* **:  :****::*. *

3500|gene|nph       KIEGIRDIRDESDRDGVRVVIECKRGSNADVVKNQLLEHHLENTFSIISLALVDDQPRVL
889|gene|nrc1       KLEGITDLRDESDRNGVRIVIDLKQKANTDVVENRLLESHLEKTFSVINLALVDGEPKVL
133|gene|hut        IIEGVSDLRDESDRDGVRVVIECKRGANVDVVENQLLDHHLESTFGVINLALVDGEPRVL
10455|gene|hma      KIEGISDLRDESDRNGVRIVVELKRGANIDVVENRLLDHHLESTFGVINLALVDGQPKVL
1180|gene|hhi       KIEGIADLRDESDRNGVRIVVELKRGANIDVVENRLLDHHLESTFGVINLALVDGQPKVL
994|gene|hla        SIEGIRDLRDESDRDGIRVVVELKRDAMAEVVKNQLLESHLERTFGVINLALVDGSPQVL
2651|gene|hwa       TIEGIRDLRDESDRDGIRVVVELKRGANPDIVKNQLLEHHLESTFGVINLALVDGQPQVL
16520|gene|hbo      KIEGIRDLRDESDRDGIRVVVELKRGANPDVVKNQLLEHHLESTFGVINLALVDGQPRVL
                     :**: *:******:*:*:*:: *. :  ::*:*.**: *** **.:*.*****..*.**

3500|gene|nph       NLKELLEAFVGHRREVVRRRSQFELQEAKDRAHILEGRLVALDNVDDVVDHIQNSDDRDA
889|gene|nrc1       TLKELLAEYVSHRKEVVRRRSEHDLGEAEDRAHILDGRLTALENADEVVELIQDAEDRDA
133|gene|hut        TLKETLEEYVAHRKEVVRRRSEFDLAEAEDRAHILEGRLKALGNVDSVVDLIRDSEDRDE
10455|gene|hma      SLKESLQHYIDHRREVVRRRSEYDLAEAEDRAHILEGRLKALENVEDVVELIRNREDRDA
1180|gene|hhi       SLKETLQHYIDHRREVVRRRSEYDLAEAEDRAHILEGRLKALENVEDVVELIQNSEDRDA
994|gene|hla        DLKQTLEYYVEHRRDVVRRRSEHELAEREDRAHILKGRLKALEQVDDVVETIQNSDDRDA
2651|gene|hwa       TLKETLHEYLEHRRTVVRRRSQYELDEKRDRAHILEGRLRALEQVDDVVDIIRNSTDRDN
16520|gene|hbo      TLKETLKEYLDHRREVVRRRSEYELGEAEDRAHILEGRLKALENIDDVVETIRNSESRDD
                     **: *  :: **. ******:.:* *  ******.*** ** : :.**: *.:  .** 

3500|gene|nph       AMAALR--------------KAYDLSEDQAEHIVRMQLGSLTSMEAGEIETEYEDVQAEI
889|gene|nrc1       AKETLK--------------SAFDFSQDQADHIVRMQLGSLTSMEAADIESEYEDVTARI
133|gene|hut        AKAALE--------------ETFDFSTEQAQHIVRMQLGSLTSMEAAEVEDEYEEVEAEI
10455|gene|hma      ARTGLQ--------------ESFDFSEEQAAHIVRMQLGSLTSMEAAEIEDEYEDVQNTI
1180|gene|hhi       ARTGLQ--------------ESFEFSEEQAAHIVRMQLGSLTSMEATEIEEEYEDVQNTI
994|gene|hla        AKAALE--------------ADYEFSEAQAEHIVRMQLGSLTSMETQEIESEYEDVTARI
2651|gene|hwa       AKAALRGEHVVESDERGESLPTFDFSEDQANHIVAMQLGSLTSLESDEIEDEYESVQERI
16520|gene|hbo      AKAALRGEMTVEVD--GEPLPTFDFSEDQANHIVAMQLGSLTSMEAAEIKDEYEEVQDRI
                    *   *                 :::*  ** *** ********:*: ::: ***.*   *

3500|gene|nph       ERLETILNDESELLGVIKDELRDIKAEYADERQTDVIEDAGSVTREDLIAEEEVVVVVTE
889|gene|nrc1       ERLEEILGSEQELLDVIKDELREIKTQYADERRTSFIEDTGTVADEDLIPEEDTVVVLSE
133|gene|hut        ERLETILNDESELLDVIKDELRAVKDEYDDDRRTSIVEDDGTVTREDLIPEEECLVVVTE
10455|gene|hma      DYLESVLNSREKLDSVIADELQEVKDDYDDDRRTSIIEDEGQVTHEDLIPEEDCVVVITE
1180|gene|hhi       DYLESVLNSREKLDSVIADELQEVKDEYGDDRRTSIIEDEGQVTHEDLIPEEDCVVVITE
994|gene|hla        ERLETILGDPDELDQVIITELREIKDEYDDERRTSFIEDVGDVTHEDLIPEEECVVVMSE
2651|gene|hwa       ERLQTILNNPDELDAVVEDELATIRDKYADERRTRIIEDDGTVTHEDLIAQEDVVVVVTE
16520|gene|hbo      DRLNEILNNPDELDAVIKSELTAIKDEYDDERRTSFIEDTGTVTHEDLIAEEDVVVVVTE
                    : *: :*.. .:*  *:  **  :. .* *:*.* .:** * *: ****.:*: :**::*

3500|gene|nph       EDYVKRMPLSEFDPQHRGGKGIIGSRPKEGDRVSTVFTASTHDYLLCFTNQGQVYRLKVF
889|gene|nrc1       GDYIKRVPAETFDAQHRGGKGIIGSDLKDGDRVSTVFTASTHDYLLCFTDQGQVYRLKVY
133|gene|hut        DDYIKRMPADRFDAQHRGGKGIIGADPKEGDRVSTVFRANTHDYLLAFTNHGQVYRLRTY
10455|gene|hma      DDYIKRMPVENFDPQNRGGKGIIGADPKENDRVSKVFRANSHDYLLCFTNQGQVYRLKTY
1180|gene|hhi       DDYIKRMPVENFDPQNRGGKGIIGADPKENDRVSKVFRANSHDYLLCFTNQGQVYRLKTY
994|gene|hla        DDYIKRMSLDTFRAQNRGGKGIIGTDLKEGDRVSSVFAANSHDYLLVFTNHGQIYELKTY
2651|gene|hwa       DDYIKRMSLEDFRSQHRGGKGIIGTSLKDGDTVSSVYVANTHDYLLYFTSHGQVYQLKTY
16520|gene|hbo      DDYIKRMPLDTFRAQHRGGKGIIGTDLKEGDRVSSVFVASTHDYLLYFTNHGQVYKLKTY
                     **:**:. . * .*:********:  *:.* **.*: *.:***** **.:**:* *..:

3500|gene|nph       ELPEMGRTARGTSAVNVLDLNDGEEITAVVNTD--DIDEG---YLAMATEAGYVKRTAVS
889|gene|nrc1       QVPEMSRTARGTSAVNILDLDDGEEISAVVTADDLDFKADDE-YLTMATRNGYVKRTSVG
133|gene|hut        EIPEMSRTARGKSAVNLINFDDGEEITAVVSMD--EFDDDE--CITMATRQGYVKRTCCS
10455|gene|hma      EIPEMSRTARGKSAINLIDLDDGEELTAVVSTD--EFGDDE--CITMVTRNGYVKRTCCS
1180|gene|hhi       EIPEMSRTARGKSAINLIDLDDGEELTAVVSTD--EFGEDE--CITMVTRNGYVKRTCCS
994|gene|hla        EIPEMSRTARGKSAVNLIDLDDGEEIEAVVNTD--DLDDDE--FLTMVTRDGYIKRTAVD
2651|gene|hwa       QIPEMSRTARGKSAVNLLELDDGEQITAVVNTAEMDIDDDEERYFTMVTQSGYIKRTSVN
16520|gene|hbo      QIPEMSRTARGKSAVNLLELDDGEEITAVVNTA--DIEDETDKYLTMATQNGYVKRTSVE
                    ::***.*****.**:*:::::***:: ***.    ::       ::*.*  **:***.  

3500|gene|nph       EFENVHAGGIRAVSLEDDDSLVDVEVTDGDGDLLVGTKHGMTIRFDESDARPMGRSARGV
889|gene|nrc1       EFGNILSTGIIAIDLEDGDALADVEVTDGSHDVILGSEAGMAIRFDEGDVRAMGRNARGV
133|gene|hut        EFENILSTGIIAAKLEDGDELVDAVVTDGESDLVIATEDGMTIRFDETEARQMGRTARGV
10455|gene|hma      EFENILSTGIIAAKLEDSDELIDVDVTDGTGDLVIATEAGMTIRFSESEVSEMGRSARGV
1180|gene|hhi       EFENILSTGIIAAKLEDGDELIDVDVTDGTGDLVIATEAGMTIRFSESEVSEMGRSARGV
994|gene|hla        QFGNIRSTGIRAIRLEDGDELVDVEVTNGGTDIVIGSRNGMAIRFAESEARAMGRTARGV
2651|gene|hwa       SFQNIRSTGIIAISLGADDKLIDVEVTDGNRDIILGTRKGMAIRFNEGDVRSVGRSARGV
16520|gene|hbo      KFQNILTTGIIATKLDEDDELADVEVTDGSHDLVLASRDGMAIRFDESDVRAMGRSARGV
                    .* *: : ** *  *  .* * *. **:*  *:::.:  **:*** * :.  :**.****

3500|gene|nph       NGIKLEGDDRATGLVAASSDDDRDLLTVTKNGYGKRTPLSEYRRQSRYGKGLVDIKTDER
889|gene|nrc1       RGMDLDAADRIAGVAAVESEDDRSLLTVTEFGYGKRTRVGEYRSQSRNGKGLVDIKTGDR
133|gene|hut        RGIDLRDGDNVAGVVATDEHDERALLTVTERGYGKRTPLSEYRTQSRYGKGLIDIKTGDR
10455|gene|hma      NGIKLQDDDKVAAMVATDDDDPRSLLTVTEHGFGKRTKLDEYRTQSRYGKGLIDIKTDDR
1180|gene|hhi       NGIKLQGDDRVAAMVATDGDDRRSLLTVTEHGFGKRTKLDEYRTQSRYGKGLIDIKTDDR
994|gene|hla        IGIDLREGDAVAGVAAIDEDRHNWVLTVTENGYGKRSDLDEYRLQSRNGKGLIDIKTGDR
2651|gene|hwa       HGIKLEDTDAVAALAAVDDDQDDWVLTVTEHGYGKRTDIDRYRQQSRNGKGLIDIKTNER
16520|gene|hbo      RGMKLEGDDELVGVAAVDEDRHNWVLTVTQNGYGKRSDIERYRRQSRNGKGLIDIKTNDR
                     *:.*   *  ..:.* .      :****: *:***: :  ** *** ****:****.:*

3500|gene|nph       NGPVCSLDAVSEDDGLVIMSESGQIMRTTVDEISTVGRNTKGVVVMSVDDDDRIAGIDVD
889|gene|nrc1       NGDVVSVDAVGDDDSLVVMSADGQIIQMPVDEISTVGRNTKGVNIMAVGSGDEVAGVSVR
133|gene|hut        NGGVTAVNAVAEDDHVIVMSATGQIMRCPVEDVSTVGRNTMGVTIMDVAADDTVASVDVI
10455|gene|hma      NGRVSTAKAVTDEDHLVIMSEQGQIMRIRAGDVSQVGRNTKGVTIMGLEEDDRVASVTVV
1180|gene|hhi       NGRVSTAKAVTDEDHLVIMSEQGQIMRIRAGDVSQVGRNTKGVTIMGLEEDDRVASVTVV
994|gene|hla        NGEAVAIEAVTYGDHLLAMSDNGQIMRTRVEEISTVGRNTKGVIVMNLDPDDTVASVDIV
2651|gene|hwa       NGHVCEVETVGISDELFMMSRKGQILRTPVDDISTVGRNTMGVIVMDLEDTDTVASVDTH
16520|gene|hbo      NGPVCAMETVGYGDHLFVMSESGQILRTPVEDISTVGRNTMGVTVMDMDEGDHVASVDVY
                    ** .   .:*   * :. **  ***:.  . ::* ***** ** :* :   * :*.:   

3500|gene|nph       SAE-------------------------------
889|gene|nrc1       AADQADGEE-------------------------
133|gene|hut        PGTAIEDS--------------------------
10455|gene|hma      PAETE-----------------------------
1180|gene|hhi       PAESEK----------------------------
994|gene|hla        SESVHGGETDVEGDE-------------------
2651|gene|hwa       PRTDDSSEADSGDGESESENATATTPS-------
16520|gene|hbo      NVGSDEVDEEASDEEAPDDETSDEDTSDEDTSTE